Insane in the Membrane

a biofizz production


Bacteriorhodopsin, Rhodopsin and GPCR's


Jan 29

Reading 1:Structure of Bacteriorhodopsin

 

 


 

Query 5

 

What is the vectorial difference between the proton pump and chloride pump and how might they be related?

 



 

Query 6

 

Why is the resolution anisotropic for the bacteriorhodopsin structure described in the paper?


 


Jan 31

Reading 2: Rhodopsin and B2Ar 

      

       


 

 

Query 7

 

Why would molecular models of B2Ar based upon the rhodopsin structure be ineffective for drug design?

 



 

Query 8

 

Why did the authors use a fusion protein of b2ar instead of the holo protein?


 


 

Stowell lab

Insane in the Membrane

Notnow notever