Bacteriorhodopsin, Rhodopsin and GPCR's

Jan 29 Reading 1:Structure of Bacteriorhodopsin

Query 5   What is the vectorial difference between the proton pump and chloride pump and how might they be related?

Query 6   Why is the resolution anisotropic for the bacteriorhodopsin structure described in the paper?

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Jan 31 Reading 2: Rhodopsin and B2Ar

Query 7   Why would molecular models of B2Ar based upon the rhodopsin structure be ineffective for drug design?

Query 8   Why did the authors use a fusion protein of b2ar instead of the holo protein?

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